Opportunity Information: Apply for RFA IP 16 002
This CDC funding opportunity (RFA IP 16 002) is a discretionary cooperative agreement focused on producing annual, U.S.-based estimates of influenza vaccine effectiveness (VE) for preventing medically attended, laboratory-confirmed influenza. The public health need behind it is straightforward: influenza viruses evolve continuously, vaccines are reformulated each year, and the country relies on vaccination as its main prevention strategy for everyone 6 months of age and older. Because both the virus and the vaccine change from season to season, decision-makers need updated, real-world VE results every year to understand how well vaccination programs are working and to guide recommendations, risk communication, and policy.
The work supported by this grant is centered on measuring how well seasonal influenza vaccines reduce the risk of getting influenza illness severe enough to prompt someone to seek medical care, with confirmation by laboratory testing. The description emphasizes outpatient, medically attended disease and aligns with a long-standing evidence base of VE evaluations for seasonal influenza and the 2009 pandemic-era vaccines, citing multiple prior studies. In practical terms, this kind of annual VE effort typically involves enrolling patients who present for care with influenza-like illness, testing them for influenza, and comparing vaccination status among those who test positive versus those who test negative to estimate vaccine performance for that season. The intended outcome is a timely, credible VE estimate that reflects the current season's circulating viruses, the current season's vaccine composition, and how vaccination performs across real-world populations.
As a cooperative agreement, the CDC expects to be substantially involved in the project rather than functioning only as a pass-through funder. That generally means recipients should be prepared for active collaboration, shared protocols or standards, coordinated reporting, and contributions to a broader national picture of influenza vaccine performance. The opportunity anticipates up to five awards, with an award ceiling of 1,000,000, indicating support for a small set of organizations capable of running robust, recurring VE evaluations with consistent methods and strong clinical and laboratory capacity.
Eligibility is broad across U.S. domestic entities, reflecting the nationwide relevance of influenza. Eligible applicants include state, county, city or township, and special district governments; independent school districts; U.S. territories or possessions; eligible federal agencies; public and private institutions of higher education; and a wide range of nonprofit organizations (including those with or without 501(c)(3) status), as well as public housing authorities/Indian housing authorities and Native American tribal governments or tribal organizations. The announcement specifically encourages applications from certain higher education institution categories that are often prioritized for federal support, including Hispanic-serving institutions, HBCUs, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian serving institutions. It also allows bona fide agents to apply on behalf of state or local governments, but only with a legal, binding agreement documenting that status.
The restrictions are also clear: foreign organizations are not eligible, foreign components of U.S. organizations are not eligible, and applicants may not include collaborators or consultants from foreign institutions under this announcement. In other words, the CDC is limiting the work to domestic institutions and domestic partnerships, consistent with the goal of generating U.S.-specific VE estimates and ensuring the project is carried out under applicable U.S. federal laws and policies.
Key administrative details included in the notice are that the sponsoring agency is the Centers for Disease Control and Prevention (CDC), the funding instrument is a cooperative agreement, the activity category is health, and the CFDA number listed is 93.185. The opportunity was created on 2015-11-05, with an original closing date of 2016-01-11, and it projected five total awards. Overall, the grant is aimed at sustaining a reliable annual pipeline of influenza vaccine effectiveness evidence so the U.S. can continuously evaluate and improve its primary influenza prevention strategy in the face of constantly changing viruses and vaccines.Apply for RFA IP 16 002
- The Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Annual Estimates of Influenza Vaccine Effectiveness for Preventing Medically Attended Laboratory-Confirmed Influenza in the United States" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.185.
- This funding opportunity was created on 2015-11-05.
- Applicants must submit their applications by 2016-01-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
- The number of recipients for this funding is limited to 5 candidate(s).
- Eligible applicants include: Others.
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| Funding Opportunity |
|---|
| Lesotho HIV Care and Treatment Services Apply for RFA 674 16 000001 Funding Number: RFA 674 16 000001 Agency: South Africa USAID-Pretoria Category: Health Funding Amount: $62,000,000 |
| Evaluating the Impact of Non-pharmaceutical Measures on the Incidence of Influenza-like Illness (ILI) among Apply for CDC RFA CK 16 005 Funding Number: CDC RFA CK 16 005 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: $500,000 |
| National Centers on Health Promotion for People with Disabilities Apply for CDC RFA DD16 1602 Funding Number: CDC RFA DD16 1602 Agency: Centers for Disease Control - NCBDDD Category: Health Funding Amount: $4,500,000 |
| Enhanced Surveillance for New Vaccine Preventable Diseases Apply for RFA IP 16 004 Funding Number: RFA IP 16 004 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,000,000 |
| Connecting Kids to Coverage Outreach and Enrollment Cooperative Agreements Apply for CMS 1Z0 16 001 Funding Number: CMS 1Z0 16 001 Agency: Centers for Medicare Medicaid Services Category: Health Funding Amount: $1,000,000 |
| National Collaboration to Support Health, Wellness and Academic Success of School-Age Children Apply for CDC RFA DP16 1601 Funding Number: CDC RFA DP16 1601 Agency: Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $600,000 |
| Support of Global Polio Eradication Initiative (GPEI) using Integrated Modeling Apply for CDC RFA GH16 1602 Funding Number: CDC RFA GH16 1602 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: Case Dependent |
| Childhood Obesity Research Demonstration 2.0 Apply for RFA DP 16 004 Funding Number: RFA DP 16 004 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $1,750,000 |
| Spatially Scalable Integrated Tick Vector/Rodent Reservoir Management to Reduce Human Risk of Exposure to Ixodes scapularis Ticks Infected with Lyme Disease Spirochetes Apply for RFA CK 16 002 Funding Number: RFA CK 16 002 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $300,000 |
| Research Grants for Preventing Violence and Violence Related Injury (R01) Apply for RFA CE 16 001 Funding Number: RFA CE 16 001 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $350,000 |
| Improving Epilepsy Programs, Services, and Outcomes through National Partnerships Apply for CDC RFA DP16 1602 Funding Number: CDC RFA DP16 1602 Agency: Centers for Disease Control - NCCDPHP Category: Health Funding Amount: $4,000,000 |
| Reinforcing Capacity at Two Centers of Excellence to Sustain the Delivery of Comprehensive HIV Clinical Services in Haiti under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1680 Funding Number: CDC RFA GH16 1680 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $3,000,000 |
| Strengthening Health Management Information Systems, Data Use and Data Quality in the Republic of Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1674 Funding Number: CDC RFA GH16 1674 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,500,000 |
| Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE): Study to Explore Early Development (SEED) 3 Apply for RFA DD 16 001 Funding Number: RFA DD 16 001 Agency: Centers for Disease Control and Prevention - ERA Category: Health Funding Amount: $800,000 |
| Technical Assistance to Host Country Public Health Institutions in Tanzania to Lead HIV Response and Develop and Sustain Systems Required to Achieve and Sustain HIV Epidemic Control under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1650 Funding Number: CDC RFA GH16 1650 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,159,375 |
| Building Capacity to Deliver High Quality HIV Prevention, Care and Treatment Services for Key Populations and People Living with HIV in the Caribbean Region under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1607 Funding Number: CDC RFA GH16 1607 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,036,000 |
| HIV Surveillance for Epidemic Control in Malawi under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1629 Funding Number: CDC RFA GH16 1629 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $700,000 |
| Assisting the Ministry of Health and Social Services (MOHSS) in Providing Critical Human Resources for Health to Achieve HIV Epidemic Control in Namibia under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1640 Funding Number: CDC RFA GH16 1640 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $8,867,471 |
| Prevention of Healthcare-Associated Tuberculosis Infection in Zimbabwe under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1673 Funding Number: CDC RFA GH16 1673 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,500,000 |
| Strengthening the HIV Services Quality Improvement and Quality Management Systems of the Ethiopian Federal Ministry of Health, Regional Health Bureaus, and Public Health Facilities under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA GH16 1614 Funding Number: CDC RFA GH16 1614 Agency: Centers for Disease Control - CGH Category: Health Funding Amount: $1,000,000 |
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