Opportunity Information: Apply for RFA AG 23 030

The NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award is a National Institutes of Health funding opportunity (RFA-AG-23-030) that uses the STTR mechanism under the R41/R42 "Industry Development Award" structure, with clinical trials listed as optional. Its central purpose is not just to advance a product-oriented research project, but to deliberately help early-career scientists build the skills, experience, and professional footing needed to move into industry and entrepreneurship. In practice, the program is designed to create a bridge from academic-style training into a small business environment by pairing research and development support with a substantial emphasis on entrepreneurial education, mentoring, and career development.

A defining feature of this FOA is that it encourages small business concerns (SBCs) to bring postdoctoral fellows and early-stage researchers into key leadership roles by supporting their hiring and salary as the project Principal Investigator/Program Director (PI/PD). The intent is twofold: to strengthen the company’s scientific workforce for product development and to accelerate the professional transition of the early-career PI/PD into an industry setting. The FOA specifically highlights postdocs and early-career researchers who already have strong research and technology discovery experience, but who want to develop an entrepreneurial skillset and pursue a career in the private sector, as the best-fit candidates to lead these projects.

Because the award is explicitly structured around the investigator’s transition into the small business, the FOA emphasizes that most of the PI/PD’s employment must be at the SBC. That requirement signals that this is not meant to be a lightly affiliated role while the investigator remains primarily in an academic appointment; instead, it is meant to anchor the investigator’s day-to-day work and professional development within the company environment where commercialization and product development are central priorities.

Eligibility is focused on small businesses as applicants. Foreign institutions (non-U.S. entities) are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible. However, foreign components as defined under the NIH Grants Policy Statement may be allowed, which typically means certain limited, well-justified elements of the work could potentially occur abroad under NIH policy, even though the applicant organization itself must be domestic and eligible.

Administratively, the opportunity is offered by the National Institutes of Health under CFDA 93.866 in the health funding category, and it is a discretionary grant. The original closing date listed for the opportunity was February 17, 2023. The posted award ceiling is $1,838,436, indicating the program can support relatively substantial development efforts when aligned with the FOA’s goals. Overall, the REDI Entrepreneurial Small Business Transition Award is best understood as an STTR-based pathway that deliberately couples product-focused R and D with structured entrepreneurial immersion, aiming to grow a capable industry-facing scientific leader while also advancing a commercialization-minded technology within a small business.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "NIA Research and Entrepreneurial Development Immersion (REDI): Entrepreneurial Small Business Transition Award (R41/R42 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.866.
  • This funding opportunity was created on 2022-07-06.
  • Applicants must submit their applications by 2023-02-17. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,838,436.00 in funding.
  • Eligible applicants include: Small businesses.
Apply for RFA AG 23 030

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